ISSN Online: 2377-424X
ISBN Print: 0-85295-345-3
International Heat Transfer Conference 10
HEAT AND MASS TRANSFER AT MICROSCALES DURING FREEZING OF BIOLOGICAL SUBSTANCE
Abstract
Simplified physicochemical model was proposed and the extra and intra-cellular ice formation, osmotic water permeation through cell membrane and other microscale behavior during the freezing of biological cell were discussed as a function of temperature considering the effect of cryoprotectant. Extending the simplified model proposed for the cell element, the freezing of the biological substances was analyzed to get basic understanding for developing the cryopreservation technique.