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International Heat Transfer Conference 15

ISSN: 2377-424X (online)
ISSN: 2377-4371 (flashdrive)

Absorption of Short-Pulsed Laser Radiation in Superficial Human Tissues: Transient vs Quasi-Steady Radiative Transfer

Jaona Harifidy Randrianalisoa
Centre de Thermique de Lyon, Institut National des Sciences Appliqués, Lyon; GRESPI - EA 4694, University of Reims Champagne-Ardenne, F-51687 Reims, France

Leonid A. Dombrovsky
Joint Institute for High Temperatures, 17A Krasnokazarmennaya Str., Moscow, 111116, Russia; Tyumen State University, 6 Volodarsky Str., Tyumen, 625003, Russia

Wojciech Lipinski
Research School of Engineering, The Australian National University, Canberra ACT 2601, Australia

Victoria Timchenko
School of Mechanical and Manufacturing Engineering, The University of New South Wales, Sydney 2052, Australia

DOI: 10.1615/IHTC15.rad.008268
pages 7095-7107


KEY WORDS: Radiation, Photon, phonon and electron transport, Bio and medical applications, Computational methods, Pulsed laser, Unsteady effects

Abstract

Transient radiative transfer effects are pertinent to thermal treatment of superficial cancer via short-pulsed laser irradiation. The transient effects become particularly important due to relatively strong scattering and long attenuation path of radiation in human tissues in the therapeutic window until the complete absorption. Our analysis is based on transport approximation for scattering phase function and the Monte Carlo method for radiative transfer. One-dimensional radiative transfer problem is considered, which was proved to be applicable for simulation of heat transfer and thermal destruction of tumors in superficial human tissues in the case of indirect heating strategy. A series of Monte Carlo calculations enables us to find the threshold of the steady-state approach applicability. In the biomedical problem under consideration, the steady-state solution for absorbed radiation power is sufficiently accurate at duration of laser pulse more than about 10 ps. The calculations for human tissues with embedded gold nanoshells, which are used to increase the local volumetric absorption of the radiation, showed that overheating of the nanoshells with respect to the ambient biological tissue is strongly dependent of the laser pulse duration. This effect is quantified for short pulses by solving the unsteady radiative transfer problem.

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