ISSN Online: 2377-424X
ISBN Print: 978-1-56700-474-8
ISBN Online: 978-1-56700-473-1
International Heat Transfer Conference 16
EFFECT ON AUTOREGULATION OF THE ATERTIAL BLOOD FLOW DURING HYPERTHERMIA
Abstrakt
The wall of arteries and arterioles contain smooth muscles which can contract or relax in the response to various
factors such as high temperature, thereby regulating the vessel lumen and flow-rate. The purpose of our study is
to formulate and investigate a novel mathematical model for describing the local autoregulation of the blood
flow with account for the viscoelastic behavior of the arterial wall under hyperthermia. The variation regulation
of blood flow rate with temperature was obtained by experiment. The temperature controlling system is designed
and dynamic blood flow is measured. The Laser Doppler was used to monitor the blood flow rate during heating
process. When heating is loaded on the mouse skin, the blood flow increased sharply at the beginning and then
fell to a constant value. The variation of the blood flow rate made the shear stress between the blood flow and
the inner arterial surface increase, which leads to the relaxation of the smooth muscle layer in the arterial wall
resulting in an increase in the artery radius and a decrease in the shear stress.