In the latest years, the method of heat transfer enhancement by generating multiple longitudinal swirling flows in the circular tube has attracted much attention. However, the multiple longitudinal swirling flows also lead to high-temperature regions on the tube wall, which may shorten the life of the heat exchanger and raise safety concerns. The constructal bifurcation pipes based on constructal design were proposed as tube inserts in previous study to improve the temperature uniformity of the tube wall without destroying multiple longitudinal swirling flows. Nevertheless, the bifurcation structure interfered the heat transfer enhancement of the core region in tube. In this study, a novel type of insert, bifurcated arc pipes (BAPs), is proposed to address this problem. The thermo-hydraulic performance of tube inserted with BAPs is numerically investigated under the laminar flow. The effects of three geometric parameters (the bifurcation angle θ, the bifurcation distance h, and the curvature ε) are explored. The results indicate that the BAPs do mitigate the interference of the bifurcation structure on heat transfer enhancement while maintaining multiple longitudinal swirling flows and improving temperature uniformity at tube wall. In the cases studied so far, the Nusselt number is increased by 6.12−7.39 times with the friction factor increasing to 5.00−6.43 times compared to the smooth tube. The efficiency evaluation coefficient (EEC) is in the range of 1.08-1.36. Furthermore, a multi-objective optimization is performed by genetic algorithm along with the artificial neural network based on the principle of exergy destruction minimization. The geometric parameters of the compromised point on the Pareto front are θ = 30.11°, h = 4.57mm, ε = 0.71, and EEC = 1.34, which prove that the principle of exergy destruction minimization is effective for design and optimization.